Forensic genetic genealogy (FGG) has proven instrumental in solving cold cases. Current methods of generating genomic data for FGG, such as whole-genome sequencing (WGS) and microarray-based genotyping, are constrained by DNA input and low quality samples. The ForenSeq® Kintelligence Kit overcomes this barrier, offering a targeted sequencing solution for low DNA inputs and highly degraded DNA samples. This white paper from Verogen provides a workflow that generates new investigative leads to help solve violent crimes and missing persons cases when other options have failed.
On April 24, 2018, forensic genetic genealogy identified one of the most prolific murderers in U.S. history—opening the floodgates. Fast forward three years and forensic genetic genealogy has been used to solve thousands of cold cases across the globe. With every lead, every relative, every name, forensic genetic genealogy is changing both people’s lives and forensic science as a whole.
In forensic and crime laboratories, capillary electrophoresis is still the "norm" for DNA analysis. However, as technology advances, next-generation
sequencing is increasingly finding its way into laboratories. Each technique is advantageous on its own, but there are some samples and cases
that call for one method over the other. Compare and contrast below to understand which works best in your workflow.