There is no known research that has attempted to use Raman spectroscopy as a pre-screening tool for assessing DNA quantity and quality for forensic casework applications.
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In a new proof-of-concept study, researchers have validated a reverse complement PCR (RC-PCR) short amplicon 85 SNP-plex panel that can be used to improve library preparation for DNA analysis of difficult samples.
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On Feb. 3, 1981, skeletal remains of a man wrapped in an electric blanket were discovered at a remote site. No identification was found with the remains, which investigators believed had been out in the elements for months.
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Jacobsen had been awaiting a retrial at home in New York since November, despite DNA evidence proving his innocence.
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The unidentified man stood between 5'3" and 5'9" and was likely between the ages of 20-40. Investigators suspect that he was possibly Native American, Asian, Hispanic or mixed race.
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Police discovered there were several pieces of evidence in the case file that could likely be tested using modern DNA technology.
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DNA evidence helped investigators match the 1985 kidnapping, sexual assault and death of a 17-year-old Florida girl to a man already serving two life sentences in Michigan on sexual assault charges.
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The new method is based on the development of aptamers, single-stranded DNA molecules capable of selectively binding to a given target.
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The DNA project identified 635 registered sex offenders who illegally failed to provide DNA samples after their criminal conviction. Ferguson’s office is working with local law enforcement to collect DNA samples from these offenders.
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The Calaveras County Sheriff’s Office Cold Case Team is working directly with criminalists from the California Department of Justice and two expert forensic anthropologists to respectfully catalog and analyze the remains to determine their viability for DNA analysis.
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