Breakthroughs in Forensic DNA Analysis Using Next-Generation Sequencing

The growing use of NGS in forensic genetic applications has resulted in the analysis of alternative markers that can complement CE-STR results for challenging samples- bones, mixtures, or degraded samples- to generate investigative leads.

Marta Diepenbroek will discuss her collaborative work with colleagues from Poland and Austria, which concerns the first genetic and phylogeographic evidence for Jewish Holocaust victims found at the former Nazi death camp in Sobibór. Diepenbroek will discuss show how forensic analysis of haploid markers can shed light on historical events. 

Jesse Cox will describe the underpinnings of an approach to deconvolute mixtures of two individuals to provide ancestry and phenotypic information via NGS for both a major and minor contributor.

In this webinar you’ll hear about:

• NGS analysis of the mitochondrial genome can be combined with CE-based Y STR markers to enable lineage determination of remains
• SNP analysis by NGS is used to deconvolute mixtures for investigative lead generation