Although every validation is different, the advice and experiences of others can help you develop your own validation plan.
While automation of extraction removes one bottleneck, it also exposes throughput limitations inherent to the rest of the sample processing workflow. The remaining processes require precision liquid handling, something the small automated extraction instruments can’t address.
The availability of small automated instruments has made automation more affordable, easier to use, simpler to implement, and has also uncovered a host of additional benefits.
Although laboratory automation holds the promise of increasing sample throughput, in practice this does not alleviate the burden on laboratory staff. Rather it shifts the focus of the analyst’s efforts from sample preparation to sample analysis.